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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa033a05b0831c8a107d2008f2e36d36dc3faf202279df7c19af1f6c8eb1d80' 
  AND token = 'jznO6eQNnh6B1U4ZaHN8XjdUdnGBdhTjmkfQLI0G5xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}