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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4e335963508f8f90fb37ad6609f43c818d7fdabed2dc785331e6d6c1eeb0eb' 
  AND token = 'smgt8U0Kx727sl0Z4rfaIk6nOXzdxqJCvkjbZ77U+Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}