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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f5def80bb1a7e70f216d1a6e4ae63184e75168859e0e460838d37ae013339b' 
  AND token = 'pTIS2XOlGY1DvEz2oTsVs2rNJ19JMmma7IxZNxdxrXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}