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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74530594a771011fe280e8bc2e2c1f6a4138b3dcf90fbebbf8c261403b4d5804' 
  AND token = '7GaTZDkO8qeWDoN6N3YQWjV/ip+NPpDvFe3we6UGDWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}