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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44aa9203b37f9cf39004ef34851678ba3348560e79c848d8f3d901d895537582' 
  AND token = 'j7MPyCATcf7Ayz4O7SPLAqR+arjPOnr5DMyD26BOTkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}