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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3544480fa80f6d3623eca0bc475794afc12db1001e195f6b23a1fbc15f408fd5' 
  AND token = 'z18zh8hAltp3eXEk7RRzdcrKWO9l6lPcWnwFqkAu+wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}