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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046c8f250c6382877845538d81ea878187b9377fbd0b64c333407443a7bd7b8e' 
  AND token = 'Ndp9p3lIwPIX0EB4DENNiHLEmujeRQXzlVW2p09zfYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}