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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf21833389cb252b604edb0c099b628e7fdee7b402f8c949e809c3fba0457704' 
  AND token = 'Y+w21rxijyuo8aVMT16mkU22kXvLH6yeaTOTnMcaG9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}