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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429dcc6365aad0dc04b8f2e64ff9bd2144562fafe77ffb4421c4a81eb9a4aa05' 
  AND token = 'YpHeeCN+1YE6Ep4Gtb9ImFpEDcceuuQsArofYgjRJA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}