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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811d2cb16c2a418eac5cd697dfb0718907de72c7fa6aede0bb0ddd8490557a98' 
  AND token = '9d+MRJPLizA1h8wgB+Rx7553TR4tPN0FvEEdyzk8OE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}