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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d5b70cd9845a672cf9df7fb9c81ded708752c6df71bc36cf8899d58dc2004a' 
  AND token = 'YWRS3MQtJqf2okdX6MQ8BNbdj6uwKGEtoeUSgCaWe84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}