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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e271319ed5d236f2026c34430a11f306f94596793acb97db288bbd763e4b880' 
  AND token = 'x7X/OsS37EPtg7dkF5nE8m6omOkFCqDeFLJmSDtsZRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}