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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6456857c867be0049bd7ef2af532d705e35527e43b9ca00861049d0ac6af442f' 
  AND token = 'kY5S82QFrWfeNPItYM/jdijhZbH1F5NZKLuvpv5lgMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}