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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cc9ea6853cc20e32d0182bfb535fed0b029f6c21f3cf0cf1bcb21c3bc1f4a8d' 
  AND token = 'MImFkNF00o/M2idrgfqTnsWAp97n3IRm95rMK0NpTvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}