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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b338d8a11b1beb2d9117d4fb943b9606357bd600b067639c0c06eccd994debf' 
  AND token = 'Mg6WqPOl0JD1vUixRAkJxT0wM/KaB2X95I4Q6xUmYV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}