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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e663ce767bdc2bf749fe2edd2d19bbad4f71f7dc4164a7dc8bf265df2d8a1b' 
  AND token = 'sB+xTYOEEFN9FpdELisEJ1gXsrg9FFqnKFzRIyhWP+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}