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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac08fc24c23db122ebf4e262f9cfb1e27114a1044d266ba422048c3eef207c1f' 
  AND token = 'txAY/poOLisMiAP5qlq4Nv9nUshsiG1j6wlYKAk1fHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}