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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac666f1ccab7d3af9e23072500174c12a1c242460b1d005bb61b2b33cb07604' 
  AND token = 'bP5O/lTOXmQbLtVrbPIP4hQzTjhxMzXhh3rdQeu+DsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}