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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32721f43b44a2692fe3b844937153bd1c3f68cd605d2b35a0d13dfd82b215914' 
  AND token = 'TYobu3bwRCfF91hN6eDnr02zGjp+0tqgUruu4N6medw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}