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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb33b874fb9abc0954ae7c8b1be3cc29c567eb1cde3b9b45d874b4c4f71d271c' 
  AND token = 'h1UY+xJujmFjiPiVU7X6yKxdymTmuRYyATmsXV+vbgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}