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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5042bb735c1b40dffbc08a82357480e9a47d5a7c04bd97aec8d28fd8108ec425' 
  AND token = 'ddmmGTJOrndWkGOBTdaSo8uHNR4EV5R2MiH8EjWr6Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}