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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c36fe18e14d3eae9b04268058e56a5e256e12d1cdf19442e12cd9daf3a8e6a' 
  AND token = 'aQPK7L9GfIY+BtrX+dXh9CrnZOEZKE62ygxgqFcHK/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}