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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a5e0cf30e465a4f77e7ba60cae76612d3c21faba2eea66698e21382d1e702f' 
  AND token = '/o9HyebZF9jc57wcj3ecYfj/e/25X6+merUxAHZ3/wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}