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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7763a8901de49617de2ca6abbe5e19306cdfbe1b3b804a3776aece48ba063a4' 
  AND token = 'cypK3VFSgRKtkEH4W5wPfQTzarzFqRE6Vm8b5e21K/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}