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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca43c797e500b24f8ef50efe7afa87cc4e0c1c177fd3b82230bf5f24c5019ff2' 
  AND token = 'JHxhtwu0tR1RC9VmhkUS8Zim5zlj0WRNvWt+c+qBrjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}