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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b101168c53f433d40446fbc8dc9b041b3e6fbf9867822a682b982f615dfe911f' 
  AND token = '6JumMac3IJutGtA5d6tOFEtSfklF02cNG8kcFGv60DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}