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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7b4193def7642c33469a5b2a0d1099d12c143426cc13c6043cfe17e65297c2' 
  AND token = '2dzg3lT5X2a9jWSV832YHR54DPW74k8Ymh3NRTxf87w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}