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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '953f4363b98db56360e37bdf89632a299a7ddbcb4447ae5464c5b0b9a547bf56' 
  AND token = '+93HK6HKs6mXLbNe+W223gK/KP9vGlmUIzUBUK0oGQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}