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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20d75ec43ca86aacc00f91c92103e92c333d9b0720a7a79b055c2e586ab6dc3c' 
  AND token = '6HZHDkoVXOv8xB4LcT3Zd8bGpkYuAsTkgcp7Z7b8mbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}