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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd8aa10cae26a22ecead9fbf1f6eec9230252bd8205df3fc58f40ff5c362439' 
  AND token = 'pPkm7UnjSqbrchwsgwsWpeBiNhONF0j2qyZGp2RDSWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}