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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0324c5c90aed9035fb176ef6abf61f2b110a9375222c18a4d1cb760170be769' 
  AND token = '3+lNNSD+SiQWC7v2UfQNpXUpNrZPq5qsVaqjT3h1yig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}