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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b588a8466b3c40030cddb3e8c195cd8120ea3296ac006cd5ef50ac07094ca001' 
  AND token = 'JwLTGSXY2lScoYJx3leparN5aRDqNaA+aogS8K8y2Kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}