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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b8df905a6f2d13f12337de1c262ceb511b972a1a4287512ae281e5a7eeaac5' 
  AND token = 'dUNIboWLtt2MC5cOocNHStmoeUCyfQolZaUe8RscOhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}