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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c1667c95ca6015e92d5da8efdd721ced4b635f6d080be3a7ca754ad7e7a235' 
  AND token = 'jKnHjzwB0rQT/f+RiiDzu70qtF2hu2d4XdUZ8f+BI/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}