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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f71beea2cb51ea1ca05616797645f67c144542546dd5b5eaf0d5e34096c9da6' 
  AND token = 'xPl5lX/f3fkwO0ZYS1Lo7Cv0PqOpu4hVXdb401pyHnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}