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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07afdf803f7f81e3fd14300e032fcdde33821aa24a3b1c22e8cd683a0beb80a2' 
  AND token = 'Lp09P1Ofnvf/i686M7iK8LYTOoXDAYuoy5B42vQmkyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}