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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67281f41d3b8b8511edbf582ed0ad8bdb0cfc4d2d8a3e0850902d75fe620077c' 
  AND token = '7YSSqeLkzyiD9AQpk5ScRqsY6M5hVSx3fk0Ic3OdLjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}