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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e139737a574e5a3632fe890270e8424ebaeffe402f4648f071624c6dddc0b1' 
  AND token = 'pORmFCvGXi50aN/Ni3b4TZg1KscyVo77qBuSELku7rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}