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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ebaeb9d8a7df5751ee55c3ae79e47ec2da8d95e487caed27f7889fa6a883c0' 
  AND token = 'qy1AoyOw4X7P5dVdu8RfcM/IbtIwt6XtDNJNaxG/ruI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}