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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34660e4cbc11ea8b6a05039495df7d5a25d31da41eea84de4729baf5e6586390' 
  AND token = 'F46JXD9f+ZhN+hMiLiS4nohEfK4lnzV0YvVDshumPp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}