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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7888bc8d3e65ea50032c17ed594741fbade1cb00fa4188c0765536b25db7355' 
  AND token = 'LFdgir5UNrXHVO/Lsrs4UhTGLtvUUpfqMMIxcbaeBUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}