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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44a780f0629a935851a64c1460ea21207f15935581c2155ed91aa3e5e9595a4' 
  AND token = 'mqJrJtWNMxVN0oMqwgChAw2WAyYFAyZQx0XiBz/9TCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}