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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ffdd2fa5c7e12eebe2e8f13811ae598fdb48a264a0ed06ee0228fbdb67c5a0a' 
  AND token = '+KWXnudKdY5IMYfqtze5faq2L0l91IHvd+Kgt/Vvy/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}