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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53043f0d613eeb60ce91651721be2613a21e06a659fdb0f5cacc8d078f8f0533' 
  AND token = '+Z2vyPphXyO+4HOybUNXrShzN8OE0B5xEYGK4cQloLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}