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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd66a937b8053ce267cc7470c6c657c368b4502277b1ad521d24d339a5d3aeb' 
  AND token = 'EV9FSZCDznoleRMM/kAWaxUOjOieZKN3y0r1wusUKxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}