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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce14e7f914aec2cd7fc52fbd7e7d65066926cf6f287467d7ab015004006d1081' 
  AND token = 'YM5j1yz7lpFsKwThtqPuLutuT6k665YgLT/KSg2r7lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}