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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c29ab2618fd75265b001789ec3b3367d1104adbaf5923adb5c66cd907c4fb06' 
  AND token = '8l5BBn/unKJCAkDw2cJYU4KEP2EeYLQ47wYkeeG9Id8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}