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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e19c9a0de7e13dabd343ba63d1be5534f2c9c261a77105478335a96165df7d' 
  AND token = '0LpP/s1BpPZi3mkz3s2NUJxPPUkCs/yJ5KYjWsIKzrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}