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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70dd8a65dbfc80d42c6cdae18051ad2279468a1db8671e6d77904933443e4a2e' 
  AND token = 'c9J21McZgejCcDhcg3CUH38VCCB01z/gIXCy2MIBmJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}