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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c35c6d5ca1cabf2768dc6e4a05150fa2ba95a06301d69f6b1a3340a3e860a59' 
  AND token = 'HAJotVTK02Wsqt6/XMjyjBIj04IX8qrB6Flapci5XL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}